Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum
نویسندگان
چکیده
منابع مشابه
Leishmaniosis (Leishmania infantum infection) in dogs.
The authors present an overview of canine leishmaniosis due to Leishmania infantum. This protozoan is transmitted by sandflies and the disease is frequently characterised by chronic evolution. Cutaneous and visceral clinical signs appear as the infection progresses. Lymph node enlargement, emaciation and skin lesions are the main signs observed in the classical forms of the disease. Control is ...
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Resistance to allopurinol in zoonotic canine leishmaniasis has been recently shown to be associated with disease relapse in naturally-infected dogs. However, information regarding the formation of resistance and its dynamics is lacking. This study describes the successful in-vitro induction of allopurinol resistance in Leishmania infantum cultured under increasing drug pressure. Allopurinol sus...
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Correlations between the genetic diversity of Leishmania infantum (syn. L. chagasi) isolates and their respective geographic origins support the theoretic assumption that visceral leishmaniasis probably originated in the Old World. Because dogs are widely considered to be the main reservoir of this disease, the present study aimed to investigate the degree of genetic divergence among 44 leishma...
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Background: Canine visceral leishmaniasis (CVL) caused by Leishmania infantum is endemic in the northwest and south of Iran. An appropriate vaccine can help to prevent and control visceral leishmaniasis in both humans and animals. Few studies have confirmed that the fucose-mannose ligand (FML) antigen of Leishmania donovani produced protective immunity in dogs against CVL. Objective: To evaluat...
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Abstract Background and Objective: Dogs have been introduced as a major reservoir of Leishmania infantum. Concerning the increased sporadic reports of humeral visceral leishmaniasis in Golestan province, we aimed to study seroepidemiology of leishmania infantum in Rural Dogs. Material and Methods: this study was conducted in 2012 - 2014 on 150 Serum samples of ru...
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ژورنال
عنوان ژورنال: Revista dos Trabalhos de Iniciação Científica da UNICAMP
سال: 2019
ISSN: 2596-1969
DOI: 10.20396/revpibic2620181376